Her first taste of fame came when her then-boyfriend, TV presenter John Leslie, was accused of raping a fellow TV presenter (the charges were subsequently dropped). Her tabloid-friendly looks and ease in front of the camera earned her a presenting job on Richard & Judy. She lost that job when a home sex video of Leslie, Titmuss and another woman found its way onto the Internet. She took up presenting on pornographic channel Television X.

Her other television work includes training as a chef on the 2004 series of Hell's Kitchen, and in 2005, she appeared on Channel 4's The Friday Night Project as a regular guest feature, and later she took part in ITV's Celebrity Love Island.

Outside of television, she has also modelled for many UK lad's mags, such as FHM, whose readers voted her #7 in FHM 100 Sexiest Women in the World 2005), and Nuts magazine. She also appears frequently in tabloid and occasionally broadsheet newspapers.

She made her West End acting debut in March 2006, playing a prostitute with a multiple personality disorder in plays by Arthur Miller to generally mediocre reviews. In a touch of irony, Abi was due to have been the subject of a theatre production herself in a musical satire entitled Being Abi, performed by students in her home county of Lincolnshire. Devised by pupils at Boston College, Lincoln in May 2006, it was scheduled for a three-day run before it was cancelled after concerns by parents of two teenage performers in the show over some of its content.